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Obesity & Diabetes Explained: The Overflow Phenomenon

Obesity & Diabetes Explained: The Overflow Phenomenon

In my last video, I talked about how despite
what some authorities may say, Type 2 diabetes does not have to be a chronic and progressive
condition as clearly evidenced by the fact that Doctors like Jason Fung, David Unwin,
Sarah Hallberg, and Ted Naiman just to name a few have been reversing people’s diabetes
with fasting or a low carb or ketogenic diet. While some people might be suspicious of a
new fad diet supposedly reversing diabetes, low carb isn’t actually new at all, nor
is the concept of using it to reverse diabetes. Dr. Richard Thomas Williamson wrote in his
1898 book “Diabetes Mellitus and Its Treatment” : that “Potatoes should be excluded from
the diet first, then bread, and gradually all carbohydrates should be cut off.” In 1797 military surgeon John Rollo released
a book that described how he treated diabetes with a carbohydrate restricted meat diet. Referring to this, Dr. Williamson wrote “Ever
since Rollo published his book on diabetes in 1797, and pointed out the value of restriction
of the carbohydrates in the food, it has been acknowledged that of all forms and methods
of treatment this dietetic one is the most important.” Interestingly, the concept of “grain avoidance”
or bìgǔ, (also known as BIGU) has been around for more than 2000 years, going back to the
Han dynasty. Someone named Wáng xuán hé wrote in around
the year 680AD that “before the times of farming, ancient people did not eat grain,
so they were long lived.” Not that this is a medical paper of course, but it’s interesting
that people were specifically avoiding grain more than a millenium ago. Eastern Jin Dynasty scholar Ge Hong claimed
that there was not one fat person among those practicing bìgǔ for spiritual reasons. Before I get into discussing recent concerns
about low carb diets, we need to look in more depth at how carbohydrate is a factor in the
development of diabetes. Based on the work of Dr. Ted Naiman, Dr. Jason Fung and Ivor
Cummins, the path to developing diabetes looks something like this: -First, something is filling up your fat cells,
making you fat. -More specifically, something isn’t just
filling your fat cells up with fat, it’s pinning that fat there and preventing it from
being pulled out of the fat cell to be burned up for energy.
-As we discussed last time, this thing filling up your fat cells is insulin. Insulin is an
anabolic hormone that has many functions, but one is that it acts as your “fat storage”
hormone and by inhibiting three important enzymes, it prevents you from burning fat. -Simply put, the more insulin you have floating
around, the harder it is to empty your fat cells and the fat builds up. “And the big question is why did you fill
up your adipocytes. Why are they all full? Is it because humans shouldn’t eat fat? No.
You filled up your fat cells, because you suck at burning fat because you eat too much
glucose… you’re eating carbs and glucose, you’re not burning fat, it accumulates, you
fill up your adipose.” -What Dr. Ted Naiman said here is easy to
follow because glucose which comes from carbohydrates raises insulin more than protein and much
more than dietary fat. However, in this presentation, Dr. Naiman talks about another phenomenon
usually called the Randle cycle. This is where independent of the action of insulin, glucose
prevents the burning of fat all by itself. And it makes sense that you’d want to preferentially
burn glucose over fat because you need to be able to quickly sort out incoming glucose
first since there’s not many places to put it. Depending on the person you can store a couple
hundred grams of glucose across your muscles and liver as glycogen, but if you don’t
empty your glycogen by from the liver by not eating carbohydrate long enough and you don’t
empty muscle glycogen by doing enough exercise, that tank of glycogen will fill up. At this point there’s nowhere to put incoming
carbohydrate, so insulin has to turn it into fat via a process called de novo lipogenesis
so it can be stored in the only place available: your fat cells. Dr. Naiman presents a model for how this works
“But as you add carbohydrates and raise glucose, you literally have to switch your metabolism
over and burn more glucose just to get rid of it. In fact if you eat enough carbohydrates
and glucose, you literally have to convert it to fat via de novo lipogenesis. Only when
carbohydrates and glucose are absent can you switch your fuel mixture over and burn fat
again.” This highlights how dietary fat can also be
very fattening, if you eat it with a enough carbohydrate because the carbohydrate will
prevent you from burning that fat and the insulin release will hold the fat in storage. So, to put this together: if you eattoo much
low fiber carbohydrate too frequently, it will interfere with your ability to burn fat
and fat will accumulate. As your fat cells get more and more filled with fat, you’ll
need more insulin to hold that fat in place, making your fasting insulin very high – kind
of like needing more force to cram more stuff in your suitcase. And these higher levels
of insulin worsen the whole cycle making you more resistant to insulin, meaning glucose
is harder to process because there’s basically nowhere to put that glucose – you can only
make energy from glucose at a certain rate, and your glycogen stores were filled up a
long time ago, so the glucose needs to be turned into fat for storage, but your fat
cells are already filled up. So at this point, where do you put the incoming glucose and
fat?? Unfortunately it just overflows into the abdominal
cavity, the liver, the muscle and the pancreas. The pancreas seems to be the last place that
the fat accumulates, and when the pancreas is stuffed with fat, the beta cells stop functioning
properly. Whereas your beta cells were initially pumping
out a ton of insulin to make everything I just mentioned happen, now that the beta cells
have become dysfunctional, they stop properly producing insulin, then your insulin levels
drop drastically meaning glucose can’t be dealt with, so you get diabetic level blood
sugar and then you’re prescribed insulin injections to keep the blood sugar down but that makes
it even harder to empty the fat cells, so the situation gets worse and worse . Keep in mind that as Ivor Cummins points out
in this talk, there are other unhealthy lifestyle factors that can worsen this insulin resistance
and worsen this whole situation – things like insufficient sleep, smoking, and poor omega-3
to omega-6 ratio. Maybe the worst is fructose, a component of table sugar that directly worsens
insulin resistance in the liver. “Soda and other sugary drinks are the only
individual food that’s actually directly linked to obesity. Everyone seems to think a day
without orange juice is like a day without sunshine. Juice is just like soda. There is
no difference. When you take fruit and you squeeze it, you throw the fiber in the garbage,
that was the good part of the fruit.” So depending on the person, they might be
fine and insulin sensitive eating spaghetti carbonara twice a day for many years if they’re
not drinking too much fruit juice or sugar sweetened sodas and have these other factors
in order. Before we move on let me present two pieces
of evidence for the overflow phenomenon. Going back to Dr. Ted Naiman’s talk, he gives
an excellent example of overstuffed fat causing insulin resistance: People with lipodystrophy.
this is a disorder where you have hardly any subcutaneous fat – So these people barely
have any space to safely store any fat. So where does new fat go? “But The visceral fat is completely maxed
out, and almost everyone with lipodystrophy has horrible insulin resistance and horrible
brittle diabetes” This could explain the peculiar situation
in Japan, where despite having a very low obesity rate of about 3.7%, their rate of
diabetes is 7.6%, only 2% lower than America’s 9.4% , but America’s obesity rate is about
30%. The people of Japan and other asian countries’ difficulty getting fat could ironically be
making them more susceptible to diabetes and insulin resistance because they have less
safe storage space for fat. So what happens if you give an insulin resistant
person a new place to store fat ? There was a study that tried just that. They got some
lipodystrophic mice with diabetes. Then Surgically implanted some fat tissue under the mouse’s
skin, and connected it to their blood supply and then, having a new place to put fat cleared
up the road block and magically cured insulin resistance in these mice. So, given all this, fixing these other factors
Ivor Cummins talked about and by fasting or going on a low carbohydrate diet so you get
the insulin down and the fat burning up would make the most sense as a line of treatment.
But, You surely saw articles about that study showing
that low carb diets are bad for longevity. Though, as Nina Teicholz points out, this
study was based on a simple fill in the dot questionnaire, similar to this one, which
queried the participants on on only 66 foods. What if you don’t happen to eat these particular
vegetables? The data gets left out. What if you eat a bunch of pizza and energy drinks,
it’s not on the list so that data is left out too. As Teicholz explains: “Further, the ARIC
participants’ eating habits were tracked only twice, from 1987-89 and 1993-95. After
1995 the study’s participants were assumed to have continued eating the same diet for
the next 15 years.” Finally, Diet questionnaires are inherently
unreliable since most people aren’t tracking precisely what they ate in what amount. Especially
in this case, you can’t hope to be precise with this kind of questionnaire. Can you remember
how many times per month you ate bananas, broccoli and chicken over the past year?? On the other hand, this study, published last
year in the same journal found the exact opposite result. The study concluded that “High carbohydrate
intake was associated with higher risk of total mortality, whereas total fat and individual
types of fat were related to lower total mortality. Total fat and types of fat were not associated
with cardiovascular disease, … whereas saturated fat had an inverse association with stroke.
Global dietary guidelines should be reconsidered in light of these findings.” Next, you may have heard that top US cardiologist
Kim Williams was saying just last month that “No one should be doing the ketogenic diet.”
His argument is based on a 2013 systematic review of 17 studies that found low-carbohydrate
diets to be associated with an increased risk of heart disease and death. So, I went ahead and took a look at these
17 studies which by the way are based on questionnaires. First of all, let me point out that none of
these studies even mentioned a ketogenic diet. One study specifically said “Our results
do not support a clear, general association between LCHP score and mortality.” And four
studies actually showed better health outcomes with carbohydrate reduction, particularly
high glycemic carbohydrates which would be the ones that raise insulin the most. Maybe most importantly, several of these studies
did not state the specific carb intakes so for those we have no idea if people are eating
an actual low carb diet or just eating “less carb than most people.” This is very important,
because many of the benefits of low carb and keto arise only when you sufficiently restrict
carbohydrate and get your insulin low enough. The ten studies that did clearly state carb
intake showed that the diets were not actually low carb or keto at all. Low carb typically
allows a maximum of 60g of carbohydrate or around 10% of your daily calories from carbs,
and the ketogenic diet only allows 5% of your calories from carbs. Two studies only went
as low as 25% of calories from carbs and the remaining seven six didn’t even get below
30% – this a three times higher carb intake than what is actually considered “low carb,”
and 6 times higher than ketogenic diet. So this data being used to criticize ketogenic
diets is not actually data on ketogenic diets or even low carb diets. On the other hand we have a study looking
at 83 obese people on a proper ketogenic diet for 24 weeks. By the way, the diet was administered
to the patients, data was not based on questionnaires. It concluded: “The present study shows the
beneficial effects of a long-term ketogenic diet. It significantly reduced the body weight
and body mass index of the patients. Furthermore, it decreased the level of triglycerides, LDL
cholesterol and blood glucose, and increased the level of HDL cholesterol. Administering
a ketogenic diet for a relatively longer period of time did not produce any significant side
effects in the patients.” And there’s plenty more studies that showcase
the beneficial effects of a ketogenic diet – I’ve put links to a couple dozen of them
in the description. So as we’ve seen, based on how diabetes
develops, a low carb or ketogenic diet would be the most logical approach to treating it,
yet people are constantly advised against it. Another approach this video unfortunately
didn’t get to touch on is fasting- this is another excellent way to lower insulin,
increase fat burning and restore insulin sensitivity. This is mentioned in Jason Fung’s book the
diabetes code. You may still have several concerns regarding
low carb or ketogenic diets and you may just now be thinking about concerns you have about
fasting. As I’ve covered many of these points in previous videos, take a look at the description
for links to relevant videos and more information. This video was brought to you by the online
community and virtual classroom Skillshare. The thing I like about Skillshare is that
it has something for everyone. I think that most people think of a low carb or keto diet
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fish by chef ken oringer really came in handy. With just a little bit of time investment
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100 Replies to “Obesity & Diabetes Explained: The Overflow Phenomenon”

  • If we can’t even trust doctors and scientists to properly quote studies then we better all learn how to read and understand research studies. Ain’t no body got time for that! At least there’s “What I’ve learned” on YouTube!

  • I am 31 years old by know. With 28 a got Biabitis melititus.
    A was ging to be a drivintecher ans diabitis should habe come in my day and expelled me from Thais Job.
    But with a drastisch change in my diet just as you descriped it in your Video a can now das that i am Curry from diabitis.
    My doctors testet me for a yeqr now and the can't finde and traces of Diabitis Typ 2 in my Body.
    I also went from 138KG to 86kg in this time^^

  • What does 'reversing by diet" really mean? Are they saying that once the individual's A1C gets back into the normal ranges they can go back to an unrestricted diet lifestyle? If not all that is happening is the diet is maintaining a chronic condition; that's not a cure. I've been diagnosed with type 2 and have lowered my A1C to the low 5s (started in the high 8s) by diet, however if I over carb or too sedentary for an extended period it shows with a spot glucose test. I don't consider that I've been curried since I still need to keep the changed behavior.

  • I like to eat meat, fish, vegetables and fruits instead of pizza, rice, bread, pasta and potatoes. Drink herbal teas, mineral water instead of coke and coffee.
    But then my food expense equals to apartment hire.
    I can't even save money.
    When I explain this to my boss and ask for a raise, he tells i am right and turns his face the other way and tries to chance the subject.

  • Five years ago my doctor told me I didn’t need carbs at all especially fruit and oatmeal. My keto diet is literally the easiest diet I’ve ever followed. I don’t even think about nor want the old stuff anymore.

  • Amazingly detailed, easy-to-understand analysis. My brother gave me Dr. Fung's book, "The Diabetes Code: Prevent and Reverse Type 2 Diabetes Naturally". SO VERY GRATEFUL for your hard work. THANKS. – Ken

  • How do you explain older Asians who ate a diet of 90% white rice and yet
    had virtually no diabetes or heart disease and much lower levels of

  • sounds like that cardiologist isworried that people are gonna be healthy and the medical industry will lose money!!!

  • Mayo Clinic and American Diabetes Assoc lie nonstop. Fasting is not a scam. Dimwitted people are not only annoying but actually dangerous.

  • Also, soda (aka Fructose Corn Syrup) goes straight to liver! 100% of it. Actually, real sugar cane sugar goes throughout your body. So, avoiding sugar is key. But avoiding soda is a must! Fructose corn syrup/fructose in any form goes 100% straight to liver. So, overflow occurs and fatty liver never gets better.

  • It has not to be progressive… but there is nothing like reversing. This term confuses a lot of pepole. If you have diabetes you will have it period. You can adjust yourself, nothing else. Go back to carbs and diabetes will come back soon.

  • I actually agree with the proposed mechanisms but not with the proposed solution (keto). What happens if somebody chronically over consumes fat? Wouldn't that also overflow, eventually, and cause diabetes? I mean, if I eat within my daily caloric requirement without chronic overconsumption, even if it includes some carbs, is it even possible to keep my insulin elevated to the level where it causes problems? Why is keto even necessary if I simply live within my energy requirements?

  • Keto is not rational for forever. But lowering the average of like 165g down to 60 or less should be normal living and easily mainained

  • Keto diet is not me. I find it too restrictive. So what I did is increasing my protein intake and I reduced a lot my carbohydrates. I try to eat my carbohydrates to have just the energy I need based on my activities. And at last I am loosing weight.

  • I think people would be better off ditching highly processed carbs and high glycemic carbs than going keto. While keto might impact the mechanism of insulin, a diet limited in fiber and micronutrients is inherently unhealthy and unsustainable. In fact, carnivore diet advocate shawn baker gave himself diabetic blood sugar levels by just eating meat – which is keto by nature.

  • Of course "America's top cardiologist" railed against the carb free diet – wonder how much he got paid for that by the sugar industry mafia??

  • A humble question, sir, please. Why do you care sharing this content? Are you, by any chance, fat? Because I am and I find this contents so illuminating that I can't help thinking, what's the catch?

  • 6 year old me: ate sandwich fillings, and threw away the bread.
    7 – 31 year old me: ate the bread under the falsely indoctrinated concept of a balanced diet.
    32 year old me: ditching bread again.

  • I read the study, and I don't agree with it bc it's based on questionnaires. However, just to correct, they did tracked participants 6 times. the last was between 2016 & 2017. It's right there on the study. What the video says about being tracked only 2 times is not right.

  • Alkalize your body. Vaccinations is the reason why diabetes is so common. If you don't think so go get f'd because it's a fact.

  • Fantastic as usual, I just found your channel and I can honestly say it was, “LOVE AT FIRST SITE!” Blessings, love and peace, Dyanne

  • Bigu means fasting in Chinese. It has nothing to do with low carb. The grain has always been the most important food source in China through out the thousands years of history.

  • Old video but if you think about it most carbohydrates are man made foods. Did our ancestors eat these? Absolutely not. These studies are funded by people who eat carbohydrates to promote selling them.

  • I am on a low carb, high bread, medium chain triglyceride, gluten free bacon, freedom range chicken diet and I have never felt better.

  • 1:20, the BiGu you mention seems more like a spiritual practice of avoiding food altogether instead of just "grains". They apparently try to achieve a state of immortality and living off of chi. For most Asian languages, the word "rice" or "grains" is synonymous to just "food" in general. Part of BiGu might be more analogous to intermittent fasting if anything.

  • can you explain to me (I'm not a native English-speaker): "inverse association with stroke". Does this mean that the more saturated fat you eat, the less chances you have to get a stroke? Is this what it means?

  • I'm surprised you didn't mention Dr. Richard K. Bernstein. He was the first doctor to systematically and aggressively treat diabetics in order to get them to have truly normal blood sugars. He was a pariah in the medical community for his opinions and treatments. He was diagnosed with type 1 at age 12 in 1946 and is currently 85 years old and still working. He is one of the few people still alive that have had diabetes from that era. He actually has a youtube channel and answers questions about diabetes every month. 🙂

  • It is the manufactures of forks, spoons and knives that caused all these fat people per the Supreme Court today. They have allowed this case too e forward.

  • I need to lose weight, because I'm a diabetic with too high A1C.. I'll try the advice in this video. I need the motivation Thanks!

  • Diabetes Mellitus is Type 1 Diabetes where the body makes no insulin. I'm type 1 and follow a very low carb diet. I need very little insulin at all.

  • IF you have diabetes ~ check our "Mastering Diabetes" It's the OIL and the FAT, you don't need to give up fruit if you give up oil

  • Actually, there's a really big difference between fruit juice and soda. Fruit juice has vitamins and minerals, etc. I'm sick of those who are so ignorant and then claim they know so much.

  • You mention increased insulin is required to 'hold fat in place'. I don't quite understand the biochemical mechanisms that enable this, can you elaborate?

  • I am a big fan of the mentioned MDs and other experts like Ivor Cumins. There ya go, the low carb diet has been around for centuries.

  • I recall before the mid 90's Diabetes Type II was not seen as a disease affecting children. After the transition to low fat high carb processed foods, that changed. Were parents preparing children before the mid 90'd more wholesome foods or did kids really start eating vastly more processed foods? I also recall K-12 schools putting some effect to give kids somewhat decent foods back then. Now it seems it is not the case from the little I read.

  • Diabetes is the fastest growing disease in the world. Mostly because no one explains it well.. I have never seen explained well..

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