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Acid Reflux causes and Treatment

Ebrotidine | Wikipedia audio article

Ebrotidine | Wikipedia audio article


Ebrotidine is an H2 receptor antagonist with
gastroprotective activity against ethanol-, aspirin- or stress-induced gastric mucosal
damage. The antisecretory properties of ebrotidine
are similar to those of ranitidine, and approximately 10-fold greater than those of cimetidine. Ebrotidine has anti-Helicobacter pylori activity
via inhibition of the urease enzyme and the proteolytic and mucolytic activities of the
bacterium. However, its activity is synergistic with
a number of antibacterial agents. Ebrotidine counteracts the inhibitory effects
of H. pylori lipopolysaccharides. Ebrotidine has been shown to be as effective
as ranitidine for the treatment of gastric or duodenal ulcers or erosive reflux oesophagitis,
with significantly better ulcer healing rates (albeit inexplicably) in those who smoke

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